Non-alcoholic Fatty Liver Disease Diagnosis, Grading and ... NAFLD Activity Score (NAS) ... the cause of NAFLD as shown in Table 3. <i>Introduction</i>. Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease globally. The majority of NAFLD patients have fatty liver without inflammation (nonalcoholic fatty liver, NAFL), whereas a minority develop steatohepatitis (nonalcoholic steatohepatitis, NASH). Only NASH and not NAFL has been considered to increase the risk for fibrosis progression. The present study ... Noninvasive hepatic fibrosis scores that predict the presence of advanced fibrosis have been developed and validated in adult patients with NAFLD. The aims of our study were to assess the utility of commonly used adult fibrosis scores in pediatric NAFLD and to develop a pediatric specific fibrosis score that can predict advanced fibrosis. 2.5 Hematoxylin and eosin staining and NAFLD activity score calculation. Hematoxylin and eosin (HE) staining was performed as described previously (Fujii et al., 2013). NAFLD activity scores (NAS) were calculated based on the criteria of Kleiner et al. (Kleiner et al., 2005) (see also Table 1). Disclosure of Financial Relationships Dawn M. Torres, MD Has disclosed relationships with an entity producing, marketing, re-selling, or distributing health care goods or services consumed by, Table 2. Summary of the effect of lifestyle interventions on NAFLD and NASH. - "Treatment of NAFLD with diet, physical activity and exercise."